(S)-1-Boc-Azetidine-2-carboxylic acid Methyl ester

(S)-1-Boc-Azetidine-2-carboxylic acid Methyl ester - Names and Identifiers

Name	(S)-N-BOC-AZETIDINE-2-CARBOXYLIC ACID METHYL ESTER
Synonyms	(S)-1-Boc-Azetidine-2-car... Methyl (2S)-1-Boc-2-azetidinecarboxylate 1-tert-butyl 2-methyl azetidine-1,2-dicarboxylate (S)-N-BOC-AZETIDINE-2-CARBOXYLIC ACID METHYL ESTER (S)-1-Boc-Azetidine-2-carboxylic acid Methyl ester 1-(tert-butyl)2-methyl(S)-azetidine-1,2-dicarboxylate (S)-1-tert-Butyl 2-Methyl azetidine-1,2-dicarboxylate 1-tert-butyl 2-Methyl (2S)-azetidine-1,2-dicarboxylate 1-tert-Butyl 2-methyl (2S)-azetidine-1,2-dicarboxylate O1-tert-Butyl O2-methyl (2S)-azetidine-1,2-dicarboxylate 1-(tert-butoxycarbonyl)-2-methylazetidine-2-carboxylic acid 1,2-Azetidinedicarboxylic acid, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)-
CAS	107020-12-2
InChI	InChI=1/C10H17NO4/c1-10(2,3)15-9(13)11-6-5-7(11)8(12)14-4/h7H,5-6H2,1-4H3

(S)-1-Boc-Azetidine-2-carboxylic acid Methyl ester - Physico-chemical Properties

Molecular Formula	C10H17NO4
Molar Mass	215.25
Density	1.152±0.06 g/cm3(Predicted)
Boling Point	269.0±33.0 °C(Predicted)
Flash Point	116.498°C
Vapor Presure	0.007mmHg at 25°C
pKa	-3.46±0.40(Predicted)
Storage Condition	2-8°C
Refractive Index	1.481

(S)-1-Boc-Azetidine-2-carboxylic acid Methyl ester - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
HS Code	29349990

(S)-1-Boc-Azetidine-2-carboxylic acid Methyl ester - Introduction

(S)-1-tert-Butoxycarbonyl-azetidine-2-carboxylic acid methyl ester, also known as (S)-urethane methyl ester, is an organic compound.

Nature:
(S)-1-tert-butoxycarbonyl-azetidine-2-carboxylic acid methyl ester is a colorless to pale yellow liquid. It has a lower boiling point and a higher melting point. It is soluble in solvents such as dimethyl sulfoxide and methylene chloride. It is a chiral molecule, capable of two enantiomers, I .e., the (S)-form and the (R)-form.

Use:
(S)-1-tert-butoxycarbonyl-azetidine-2-carboxylic acid methyl ester is an important organic synthesis intermediate. It can be used to synthesize biologically active compounds, such as antibacterial drugs, enantioselective catalysts, etc. It is also widely used in synthetic drugs, pesticides and materials science.

Preparation Method:
(S)-1-tert-butoxycarbonyl-azetidine -2-carboxylic acid methyl ester has many preparation methods. One common method is to react (S)-2-methyl-azetidinol with methyl formate, and carry out esterification reaction under appropriate conditions to generate the target product.

Safety Information:
Specific hazard data for (S)-1-tert-butoxycarbonyl-azetidine-2-carboxylic acid methyl ester may be limited, but in general, care should be taken to follow laboratory safety procedures when using and handling organic compounds to avoid contact with its skin, eyes, and respiratory tract. It may be a potential health hazard, so necessary personal protective measures should be taken during use, such as wearing gloves, goggles and respiratory protection. If there is an accident, should immediately take the corresponding first aid measures, and turn to professionals.

Last Update：2024-04-09 20:49:11